Overview

This book deals with a novel aspect of a topical problem that is of widespread concern. Obesity and other eating disorders are significant human health problems that are proving highly resistant to prevention and cure. The recognition of important genotype/environment interaction in the causation of these problems and of the extensive genetic homology of higher animals justifies the importance of cross-species comparisons. The book covers observations made on animals in the wild as well as experimental data on laboratory animals and farm animals in order to lay out the basic genetic and environmental factors underlying the control of appetite (including diet selection) and body weight. Breakdown in these intricate mechanisms are then compared to examine the possible common candidate genes and their interaction with non-genetic factors, particularly the availability of diet choice and of levels of body activity. Animals have much to tell us about these mysteries and may significantly aid progress in dealing with what are still highly intractable and serious diseases of the modern world.

Full Product Details

Author:   J.B. Owen ,  J.L. Treasure ,  D.A. Collier
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of hardcover 1st ed. 2001
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.50cm
Weight:   0.454kg
ISBN:  

9789048157433

ISBN 10:   9048157439
Pages:   252
Publication Date:   01 December 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

1 Human disorders of eating behaviour and body composition.- 1 Obesity syndromes.- 2 The spectrum of eating disorders in humans.- 3 Free-choice diet selection — the economics of eating.- 2 Diet selection and aberrations of body composition.- 4 Diet selection in wild animals.- 5 The animal within: lessons from the feeding behaviour of farm animals.- 6 Exercise and diet-induced obesity in mice.- 3 Genetic models of animal obesity.- 7 The obesity (ob) gene and leptin in animal models of obesity.- 8 Genetic susceptibility of rodents to diet-induced obesity.- 4 Genetic susceptibility to leanness in animals.- 9 Muscle enhanced traits in cattle and sheep.- 10 The halothane gene and leanness and stress susceptibility in pigs.- 5 Anorexia models.- 11 The Anorexia Mouse.- 12 Anorexia-like wasting syndromes in pigs.- 13 Laboratory animal models for investigating the mechanisms and function of parasite-induced anorexia.- Conclusion Implications for understanding and treating human eating disorders.

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