Free Delivery Over $100
|
|
|||
|
||||
OverviewThe androgen receptor (AR) mediates a wide range of physiological actions of androgens in cells and tissues. Contributions to this volume cover distinct topics of AR signalling, extending from the structural aspects of AR to its role in androgen-associated diseases and potential clinical applications. Some key issues covered include an overview of structural aspects of AR genes and proteins in mammalian and non-mammalian vertebrate species and a description of the identified AR splice variants in pathological and non-pathological conditions. The structural and functional analysis of coding and untranslated regions of AR are discussed in the context of diseases such as androgen insensitivity syndrome, spinal and bulbar muscular atrophy, polycystic ovarian syndrome and breast, ovary and prostate cancers. The role of AR regulated genes implicated in prostate cancer progression is also explored. This book is a comprehensive conceptual review of the recent findings on AR genes and protein structure, molecular variants, ligands, target genes and signalling mechanisms. Graduate students, scientists and professionals can use it as both a study text and a reference for research purposes. Full Product DetailsAuthor: Silvia SocorroPublisher: Nova Science Publishers Inc Imprint: Nova Science Publishers Inc Weight: 0.450kg ISBN: 9781629486932ISBN 10: 1629486930 Pages: 173 Publication Date: 01 March 2014 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsPreface; Androgen Receptors in Non-Mammalian Vertebrates: Structure & Function; Naturally Occurring Androgen Receptor Splice Variants: Impact on Androgen Signaling Pathways; Structural & Functional Analysis of the Androgen Receptor in Disease; Androgen Receptor Signaling in Prostate Cancer: Genetic & Molecular Aspects; The Role of Androgen Receptor-Regulated Genes in Prostate Cancer Progression; Computational Prediction of Regulatory Regions of the Androgen Receptor Messenger RNA; Androgens & the Ovary; Index.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
||||
