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OverviewAdvances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care. Table of Contents Front Matter Summary 1 Introduction 2 Genetic Testing 3 Genetic Test Assessment 4 Evidence 5 An Evidence Framework for Genetic Testi Appendix A: Understanding Genetic Variance and Phenotype Expression Appendix B: The GETT Checklist Appendix C: Using Evidence to Inform Clinical and Policy Decisions References Glossary Full Product DetailsAuthor: National Academies of Sciences, Engineering, and Medicine , Health and Medicine Division , Board on Health Care Services , Board on the Health of Select PopulationsPublisher: National Academies Press Imprint: National Academies Press ISBN: 9780309453295ISBN 10: 0309453291 Pages: 148 Publication Date: 21 April 2017 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |