Overview

Alzheimer's disease (AD) is a devastating neurodegenerative disorder affecting millions worldwide. Understanding its complex biology is essential for clinicians, researchers, and students seeking to combat cognitive decline and memory loss. This comprehensive guide provides an in-depth exploration of Alzheimer's disease, covering everything from genetic and environmental risk factors to amyloid-beta and tau pathology, synaptic dysfunction, neuroinflammation, and mitochondrial impairment. Each chapter presents clear, evidence-based insights into the molecular mechanisms driving the disease and connects them to clinical features, diagnostic strategies, and therapeutic approaches. Highlights include: Detailed discussion of amyloid and tau biology Insights into neurotransmitter imbalances, synaptic dysfunction, and cognitive decline Coverage of sleep disturbances, circadian rhythm disruptions, and lifestyle influences Current and emerging therapies, from pharmacological interventions to gene therapy and regenerative approaches Practical integration of biomarkers, imaging techniques, and personalized medicine strategies Designed for medical students, healthcare professionals, and researchers, this book is both a comprehensive reference and a practical guide to understanding and managing Alzheimer's disease. Whether for study, research, or clinical practice, this volume equips readers with the knowledge and insights needed to understand Alzheimer's disease and explore innovative therapeutic avenues.

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