Agrobacterium: From Biology to Biotechnology

Author:   Tzvi Tzfira ,  Vitaly Citovsky
Publisher:   Springer-Verlag New York Inc.
Edition:   2008 ed.
ISBN:  

9780387722894


Pages:   750
Publication Date:   01 February 2008
Format:   Hardback
Availability:   In Print   Availability explained
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Agrobacterium: From Biology to Biotechnology


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Overview

Agrobacterium is a plant pathogen which causes the “crown-gall” disease, a neoplastic growth that results from the transfer of a well-defined DNA segment (“transferred DNA”, or “T-DNA”) from the bacterial Ti (tumor-inducing) plasmid to the host cell, its integration into the host genome, and the expression of oncogenes contained on the T-DNA. The molecular machinery, needed for T-DNA generation and transport into the host cell and encoded by a series of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the subject of numerous studies over the past several decades. Today, Agrobacterium is the tool of choice for plant genetic engineering with an ever expanding host range that includes many commercially important crops, flowers, and tree species. Furthermore, its recent application for the genetic transformation of non-plant species, from yeast to cultivated mushrooms and even to human cells, promises this bacterium a unique place in the future of biotechnological applications. The book is a comprehensive volume describing Agrobacterium's biology, interactions with host species, and uses for genetic engineering.

Full Product Details

Author:   Tzvi Tzfira ,  Vitaly Citovsky
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2008 ed.
Dimensions:   Width: 15.50cm , Height: 4.10cm , Length: 23.50cm
Weight:   2.800kg
ISBN:  

9780387722894


ISBN 10:   0387722890
Pages:   750
Publication Date:   01 February 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Reviews

From the reviews: <p> A compilation of many aspects of Agrobacterium research, with each chapter authored by experts in the field. Though the book is heavily oriented toward the genetic/molecular basis of the gene transfer process, it includes the history of Agrobacterium research, nomenclature, and basic biology of the bacterial/plant interaction. The final chapters review bioethics and legal aspects of Agrobacterium-mediated gene transfer. Summing Up: Recommended. Graduate students and researchers/faculty. (L. M. Baird, CHOICE, Vol. 45 (11), August, 2008)


Author Information

Dr. Tzvi Tzfira is an Assistant Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of Michigan. Dr. Vitaly Citovsky is a Professor in the Department of Biochemistry and Cell Biology at Stony Brook University.

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