Advancements of Mass Spectrometry in Biomedical Research

Author:   Alisa G. Woods ,  Costel C. Darie
Publisher:   Springer Nature Switzerland AG
Edition:   2nd ed. 2019
Volume:   1140
ISBN:  

9783030159528


Pages:   813
Publication Date:   09 August 2020
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Advancements of Mass Spectrometry in Biomedical Research


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Author:   Alisa G. Woods ,  Costel C. Darie
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   2nd ed. 2019
Volume:   1140
Weight:   2.033kg
ISBN:  

9783030159528


ISBN 10:   3030159523
Pages:   813
Publication Date:   09 August 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Mass Spectrometry for Proteomics-based Investigation 2. MALDI profiling and applications in medicine 3. Applications of Matrix-Assisted Laser Desorption Ionization In-Source Decay Mass Spectrometry 4. Proteome imaging: from classic to modern mass spectrometry-based molecular histology 5. Mass Spectrometry-Based Tissue Imaging of Small Molecules 6. Sequencing Proteins from Bottom to Top: Combining Techniques for Full Sequence Analysis of Glucokinase 7. Proteomics and non-proteomics approaches to study stable and transient protein-protein interactions 8. Contribution of Mass spectrometry-based Proteomics to Discoveries in Developmental Biology 9. Profiling optimal conditions for capturing EDEM proteins complexes in melanoma using mass spectrometry 10. The Methods employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein-Protein Interactions (PPIs) 11. Identification of post-translational modifications (PTMs) of proteins by mass spectrometry 12. Sequence Variant and Post-translational Modification Analysis During Cell Line Selection via High-throughput Peptide Mapping 13. Selective derivatization of hexahistidine-tagged recombinant proteins 14. Investigation of Antibody-Drug Conjugates by Mass Spectrometry 15. Mass Spectrometry- and Computational Structural Biology-Based Investigation of Proteins and Peptides 16. Strategies for Membrane Protein Analysis by Mass Spectrometry 17. The Potential for Ion Mobility in Pharmaceutical and Clinical Analyses 18. Application of Ion Mobility Mass Spectrometry in Lipidomics 19. Mass Spectrometry in Advancement of Redox Precision Medicine 20. Applications for mass spectrometry in the study of ion channel structure and function 21. Immuno - affinity Mass Spectrometry: A Novel Approaches with Biomedical Relevance 22. Developing well-annotated species-specific protein databases using comparative proteogenomics 23. Stoichiometry of heavy metal binding to peptides involved in Alzheimer's disease: mass spectrometric evidence 24. Role of mass spectrometry in investigating a novel protein: the example of Tumor Differentiation Factor (TDF) 25. Mass Spectrometry-Based Biomarkers in Drug Developmen 26. Combinatorial Electrophoresis and Mass Spectrometry-Based Proteomics in Breast Milk for Breast Cancer Biomarker Discovery 27. Proteomic approaches to dissect neuronal signalling pathways 28. Mass Spectrometry for the Study of Autism and Neurodevelopmental Disorders 29. Simplifying the proteome: Analytical strategies for improving peak capacity 30. Exploration of nicotine metabolism in Paenarthrobacter nicotinovorans pAO1 by microbial proteomics 31. Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) for Quantitative Proteomics 32. Mass spectrometry based comparative proteomics using one dimensional and two dimensional SDS-PAGE of rat atria induced with obstructive sleep apnea 33. 2D SDS PAGE in combination with western blotting and mass spectrometry is a robust method for protein analysis with many applications. 34. Pulse SILAC approaches to the measurement of cellular dynamics 35. Protein Biomarkers in Major Depressive Disorder: an Update 36. A Pilot Exploratory Proteomics Investigation of Mental Fatigue and Mental Energy 37. Metabolomics and biomarker discovery 38. Analytical Methods for Mass Spectrometry-Based Metabolomics Studies 39. Trends in analysis of cortisol and its derivatives 40. Detection of biomedically relevant stilbenes from wines by mass spectrometry 41. Mass spectrometry as a complementary approach for noncovalently bound complexes based on cyclodextrins 42. Trends in glycolipid biomarker discovery in neurodegenerative disorders by mass spectrometry 43. Non-targeted Screening in Environmental Monitoring Programs 44. Mass Spectrometric DNA Adduct Quantification by Multiple Reaction Monitoring and its Future Use for the Molecular Epidemiology of Cancer 45. Bottlenecks in proteomics: an update 46. Recent Applications of Mass Spectrometry at Clarkson University Index

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Dr. Costel C. Darie started his biomedical career as a nurse at the Murgeni Hospital, Romania. He received his BS and MS in biochemistry at the Alexandru Ioan Cuza University from Iasi, Romania, and performed research under Dr. Vlad Artenie. He continued his Ph.D. studies with Dr. Wolfgang Haehnel at the Albert-Ludwigs Universitaet, Freiburg, Germany, after which he worked in the labs of Drs. Paul M. Wassarman & Micsunica Platica (Mount Sinai School of Medicine) and Thomas A. Neubert (New York University Medical Center). He currently is an Associate Professor of Chemistry and Biomolecular Science at Clarkson University, where he is the lead of the Biochemistry and Proteomics Group. Dr. Alisa Woods received her BS in psychology from the State University of New York (SUNY) at Plattsburgh and her PhD in biology from the University of California, Irvine, with Dr. Christine Gall. She continued with post-doctoral training at the University of Freiburg, Germany, with Dr. Michael Frotscher and completed a Master's degree in Mental Health Counseling at the University of Massachusetts, Boston. She is currently a Research Associate Professor of Chemistry and Biomolecular Science at Clarkson University, where she works in the Laboratory for Biochemistry and Proteomics.

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