Overview

There is hardly an area of research developing so quickly and raising so many promises as stem cell research. Adult, embryonic and recently available induced pluripotent stem cells not only foster our understanding of differentiation of endo-, ecto- and mesodermal lineages to all organs of the body, but foremost nourish the hope that cells grown in culture can be used for regeneration of diseased organs such as the heart damaged by myocardial infarction. This book focuses on perspectives of stem cells for regenerative therapy of cardiovascular diseases. Based on the EC consortium INELPY, it reviews the field and disseminates major outcomes of this project. Thus it introduces the reader to this fascinating area of research and incorporates very recent findings interesting to the expert, spanning the field from bench to bedside. The compilation of contributions is unique as there is yet no similar comprehensive overview combining stem cell research with preclinical and clinical evaluation as well as engineering of tissue patches for transplantation. As such it will be an invaluable source of information for all researchers in the stem cell and tissue regeneration field including bioengineers as well as for all clinicians interested in regenerative therapies, especially for ischemic cardiomyopathies.

Full Product Details

Author:   Jürgen Hescheler ,  Erhard Hofer
Publisher:   Springer
Imprint:   Springer
Edition:   2014 ed.
Dimensions:   Width: 15.50cm , Height: 1.50cm , Length: 23.50cm
Weight:   4.359kg
ISBN:  

9789401786560

ISBN 10:   9401786569
Pages:   170
Publication Date:   06 May 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

General Introduction.- The Infarct Cell Therapy (INELPY) consortium.- Mesenchymal stem cells for cardiac repair: preclinical models of disease.- Resident cardiac progenitor cells.- Endothelial progenitor cells derived from cord or peripheral blood and their potential for regenerative therapies.- Adipose-derived stromal/stem cells and their differentiation potential into the endothelial lineage.- Cardiac cell replacement therapy with pluripotent stem cell-derived cardiomyocytes.- Biomaterials for cardiac tissue engineering and regeneration.- Cell therapy of acute myocardial infarction and ischemic cardiomyopathy: from experimental findings to clinical trials.- Clinical gene and stem cell therapy in patients with acute and chronic myocardial ischemia.- Index.

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