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OverviewFull Product DetailsAuthor: David T. Curiel (Washington University School of Medicine, St. Louis, MO, USA) , Joanne T. Douglas (University of Alabama, Birmingham, U.S.A.) , David T. Curiel (Washington University School of Medicine, St. Louis, MO, USA) , David T. Curiel (Washington University School of Medicine, St. Louis, MO, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Dimensions: Width: 15.20cm , Height: 3.40cm , Length: 22.90cm Weight: 1.070kg ISBN: 9780121995041ISBN 10: 0121995046 Pages: 890 Publication Date: 28 May 2002 Audience: Professional and scholarly , Professional & Vocational Replaced By: 9780128002766 Format: Hardback Publisher's Status: Out of Print Availability: In Print  Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of Contents"Adenovirus Structure Biology of Adenovirus Cell Entry Adenovirus Replication Adenoviral Vector Construction I: Mammalian Systems Adenoviral Vector Construction II: Bacterial Systems Propagation of Adenoviral Vectors: Use of PER.C6 Cells Purification of Adenovirus Targeted Adenoviral Vectors I: Transductional Targeting Targeted Adenoviral Vectors II: Transcriptional Targeting Development of Attenuated Replication Competent Adenoviruses ARCAs) for the treatment of Prostate Cancer Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer Innate Immune Responses to in Vivo Adenovirus Infection Humoral Immune Response Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy High-Capacity ""Gutless"" Adenoviral Vectors: Technical Aspects and Applications Xenogenic Adenoviral Vectors Hybrid Adenoviral Vectors Utility of Adenoviral Vectors in Animal Models of Human Disease I: Cancer Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations Imaging Adenovirus-Medicated Gene Transfer"ReviewsThis is a well organized collection of reviews written by authorities in the field that covers key aspects in the use of adenovirus as a gene transfer vehicle. The complete coverage of so many different aspects of adenovirus vector biology will be invaluable to scientists beginning or well established in this rapidly changing field. --DOODY'S (March 2003) This is a well organized collection of reviews written by authorities in the field that covers key aspects in the use of adenovirus as a gene transfer vehicle. The complete coverage of so many different aspects of adenovirus vector biology will be invaluable to scientists beginning or well established in this rapidly changing field. --DOODY'S (March 2003) This is a well organized collection of reviews written by authorities in the field that covers key aspects in the use of adenovirus as a gene transfer vehicle. The complete coverage of so many different aspects of adenovirus vector biology will be invaluable to scientists beginning or well established in this rapidly changing field. --DOODY'S (March 2003) Author InformationDavid T. Curiel, M.D., Ph.D. is the Director of the Cancer Biology Division of the Department of Radiation Oncology at Washington University School of Medicine. Dr. Curiel graduated medical school at Emory University in 1982, where he also completed his internship and residency in Internal Medicine. Dr. Curiel’s scientific training includes tenureship at the National Institutes of Health in Bethesda, Maryland at the Pulmonary Branch of the Heart and Lung, and Blood Institute (NHLBI) from 1985-1989, and a fellowship in Biotechnology at the National Cancer Institute, Navy Medical Oncology Branch from 1989-1990. He received his Ph.D. from University of Groningen in The Netherlands in 2002. Dr. Curiel has been at Washington University School of Medicine since 2011. In addition to his role as Director of the Cancer Biology Division, he is Director of the Biologic Therapeutics Center. Tab Content 6Author Website:Countries AvailableAll regions |
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