Acute Lung Injury and Repair: Scientific Fundamentals and Methods

Author:   Lynn M. Schnapp ,  Carol Feghali-Bostwick
Publisher:   Birkhauser Verlag AG
Edition:   1st ed. 2017
ISBN:  

9783319465258


Pages:   185
Publication Date:   14 November 2016
Format:   Hardback
Availability:   In Print   Availability explained
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Acute Lung Injury and Repair: Scientific Fundamentals and Methods


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Overview

Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population  Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive.  This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair.  Special emphasis is given to state of the art techniques and methods and relevance to human disease.  Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies. ​

Full Product Details

Author:   Lynn M. Schnapp ,  Carol Feghali-Bostwick
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   1st ed. 2017
Dimensions:   Width: 15.50cm , Height: 1.30cm , Length: 23.50cm
Weight:   4.203kg
ISBN:  

9783319465258


ISBN 10:   3319465252
Pages:   185
Publication Date:   14 November 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Methods to Study Lung Injury and Repair.- Mouse Models of Acute Lung Injury.- Transgenic Animal Models in Lung Research.-  Fundamental Methods for Analysis of Acute Lung Injury in Mice.- Invasive Measurement of Pulmonary Function in Mice.- Analysis of Epithelial Injury and Repair.- Flow Cytometric Evaluation of Acute Lung Injury and Repair.- Lung Imaging in Animal Models.- Genetic and Genomic Approaches to Acute Lung Injury.- MicroRNA Analysis in Acute Lung Injury.

Reviews

Basic scientists and clinician investigators with an interest in ARDS are an appropriate audience for this work, which features contributions from clinicians and basic scientists in pulmonary and critical care from academic institutions ... . This is an excellent introduction to work in an area of great interest to intensivists. Investigators needing to understand approaches to an important clinical problem and clinicians needing a better understanding of relevant experimental methods will enjoy and benefit from this book. (David J. Dries, Doody's Book Reviews, January, 2017)


Author Information

Lynn M. Schnapp, MD Pulmonary, Critical Care, Allergy and Sleep Medicine Medical University of South Carolina Charleston, SC, USA   Carol Feghali-Bostwick, PhD Rheumatology and Immunology Medical University of South Carolina Charleston, SC, USA

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