Overview

A Probabilistic Model of the Genotype/Phenotype Relationship provides a new hypothesis on the relationship between genotype and phenotype. The main idea of the book is that this relationship is probabilistic, in other words, the genotype does not fully explain the phenotype. This idea is developed and discussed using the current knowledge on complex genetic diseases, phenotypic plasticity, canalization and others.

Full Product Details

Author:   Jean-Pierre Hugot (Université Paris Diderot Sobonne Paris-Cité; and Head, Department of Pediatric Gastroenterology, Robert Debré Hospital, Paris, France) ,  Clare Davis
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
Weight:   0.430kg
ISBN:  

9781138320727

ISBN 10:   1138320722
Pages:   186
Publication Date:   24 July 2018
Audience:   College/higher education ,  General/trade ,  Tertiary & Higher Education ,  General
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1.Introduction: complex genetic diseases. Part 1: The Genotype / Phenotype Relationship. 2. Genetic program and self-organization. 3. The share of the environment. 4. Analogy between organisms and particles. 5. Phenotypic Plasticity. 6. Behavior. Part2: Heredity. 7. Reproduction and Phenotypic Canalization. 8. Fertilization and overlapping of genotypes. 9. Nature of canalization. 10.Canalization : experimental data. 11. Implications of canalization. 12. Canalization and instinct. Part 3: Evolution. 13. Limits to naturalselection. 14. Instinct and evolution. 15. Biological function. 16. Differentiation and phenotypic coherence. 17. Speciation. 18.Phenotypic innovation. 19. Conclusion. 20. In summary. 21. Bibliography.

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