Overview

This volume bridges the gap between standard genetics textbooks and highly specialised, technical, and advanced treatments of the subdisciplines. It provides an affordable and up-to-date introduction to the field that is suited to advanced undergraduate or early graduate courses. Bioinformatic principles and experimental strategies are explained side-by-side with the experimental methods, establishing a framework that allows teachers to explore topics and the literature at their own pace.

Full Product Details

Author:   Greg Gibson ,  Spencer Muse
Publisher:   Sinauer Associates Inc.,U.S.
Imprint:   Sinauer Associates Inc.,U.S.
Weight:   0.713kg
ISBN:  

9780878932344

ISBN 10:   0878932348
Pages:   355
Publication Date:   07 January 2002
Audience:   College/higher education ,  Undergraduate ,  Postgraduate, Research & Scholarly
Replaced By:   9780878932320
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

PART 1: GENOME PROJECTS: ORGANIZATION AND OBJECTIVES - The Human Genome Project - Animal Genome Projects - Plant Genome Projects - Microbial Genome Projects - Boxes - Flat File and Relational Databases - GenBank Files - PART 2: GENOME SEQUENCING AND ANNOTATION - Automated Sequencing - Genome Sequencing - Genome Annotation - Clustering of Gene Families - Boxes - Alignment Algorithms and Tools - BLAST and Alignment Implementation - Hidden Markov Models and Gene Finding - Fundamentals of Phylogenetic Methods - PART 3: GENE EXPRESSION AND THE TRANSCRIPTOME - Parallel Analysis of Gene Expression: Microarrays and Oligonucleotide Arrays SAGE, Microbeads, and Differential Display - Gene-by-Gene Analysis - Properties of Transcriptomes - Boxes - Image Extraction for Microarray Analysis - Clustering Methods - Identification of Regulatory Motifs - PART 4: PROTEOMICS AND FUNCTIONAL GENOMICS - Functional Proteomics - Structural Proteomics - Protein Interaction Maps - High Throughput Forward and Reverse Genetics - Boxes - Domain Profiling - Construction of Transgenic Animals and Plants - PART 5: SNPs AND VARIATION - Single-Nucleotide Polymorphisms - Applications of SNP Technology - SNP Discovery - SNP Genotyping - Boxes - Linkage Disequilibrium Measures - Population-based Association Statistics - Transmission Disequilibrium Test Statistics - PART 6: COMPUTATIONAL GENOMICS - Metabolomics - In silico Genomics

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Author Information

GREG GIBSON, North Carolina State University. - SPENCER MUSE, North Carolina State University.

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