Overview

To understand and improve the underlying principles that govern how organic reactions occur, A Foundation Course for College Organic Chemistry follows a brick-by-brick building approach. Emphasis is given to interrelating experimental facts and findings with predictions (mechanism) and inferences (results). Discussions focus on clarifying how complex organic reactions occur, which is based on electronegativity differences, movement of electrons (through σ framework or π bonds), and addition or removal of atoms (hydrogen, halogens) or groups (hydroxy, amino). The book begins with simple rules governing the deconstruction of reactions and applies them to explain how esterification, amide, and cyanide hydrolysis reactions proceed. The importance of stereochemistry (used in drug development, biology, and medicine), aromatic electrophilic and nucleophilic substitutions, reaction kinetics, and dynamics is explained with suitable examples. Features: A systematic and structured approach is used to study all aspects of reactive intermediates (generation, structure, geometry, and reactions of carbocations, carbanions, and carbon-free radicals) This book incorporates scientific methods to deduce reaction mechanisms with simple and relevant explanations, and limitations A proper explanation is given to understand the influence of functional groups on the stability and reactivity of intermediates, pKa, HSAB principles, structure-activity relations, and how these can be exploited in organic chemistry Information is presented in an accessible way for students, teachers, researchers, and scientists

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9781032631141

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B. S. Balaji is Chairperson of Special Center for E‑learning and a Professor in the School of Biotechnology at Jawaharlal Nehru University. He is an award‑winning chemistry educator, has published various research papers, has developed 3D‑printed Braille models to teach chemistry concepts to BLV students, is a resource person (ICT) for Malaviya Mission Teacher training program of UGC, is a Member of Technical Expert Committee, and is in the Interface Expert Committee to assess the NON‑SWAYAM Learning Platforms of HEI for UGC‑DEB.

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