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OverviewFull Product DetailsAuthor: Krishnarao Appasani , Raghu Kiran AppasaniPublisher: Cambridge University Press Imprint: Cambridge University Press Edition: New edition Dimensions: Width: 17.40cm , Height: 1.50cm , Length: 25.00cm Weight: 0.500kg ISBN: 9781108423366ISBN 10: 1108423361 Pages: 550 Publication Date: 26 May 2022 Audience: Professional and scholarly , College/higher education , Professional & Vocational , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsPreface; I. Super Resolution Microscopy and Molecular Imaging Techniques to Probe Biology: 1. Introduction on Single Molecule Science Krishnarao Appasani and Raghu K. Appasani; 2. One molecule, two molecules, red molecules, blue molecules: Methods for quantifying localization microscopy data George Patterson and Gaetan G. Herbomel; 3. Muti-scale fluorescence imaging Ruben Bulkescher, Inn Chung, Jan Philipp Eberle, Holger Erfle, Manuel Gunkel, Jürgen Reymann, Karsten Rippe, Guido Sauter, Ronald Simon and Vytaute Starkuviene; 4. Long-read single-molecule optical maps Assaf Grunwald, Yael Michaeli and Yuval Ebenstein; II. Protein Folding, Structure, Confirmation and Dynamics: 5. Single-molecule mechanics of protein nanomachines Gabriel Žoldák and Katarzyna Tych; 6. Post-translational Protein Translocation Through Membranes at the Single Molecule Level Diego Quiroga-Roger, Hilda M. Alfaro-Valdés and Christian A.M. Wilson Moya; III. Mapping DNA Molecules at Single Molecule Level: 7. Observing Dynamic states of single molecule DNA and Proteins using Atomic Force Microscope Jingqiang Li, Sithara Wijeratne and Ching-Hwa Kiang; 8. Atomic Force Microscopy and Detecting a DNA Biomarker of a Few Copies without Amplification Sourav Mishra, Yoonhee Lee and Joon Won Park; IV. Single Molecule Biology to Study Gene Expression: 9. Single molecule detection in the study of gene expression Vipin Kumar, Simon Leclerc and Yuichi Taniguchi.Reviews'Single-molecule experiments have revolutionized our approaches to biophysics and biochemistry at molecular scales. Only a handful of reference textbooks serves the ever-expanding community of practitioners, beginners, and curious amateurs of single-molecule techniques. This volume is poised to become a new single-molecule reference work, to be readily at hand in any bioscience laboratory, to be read and understood by any scientist practicing, or simply interested, in the new world of experiments, reasoning, and statistical analysis opened up by single-molecule science.' Michel A. G. J. Orrit, Professor of Spectroscopy of Molecules in Condensed Matter, Leiden University, The Netherlands 'An excellent collection of cutting-edge reports related to single-molecule spectrometry and imaging that consists of widespread contents from basic to application; both students [and] experts will find an extended application of the technologies to biological and clinical research.' Akira Watanabe, Assistant Professor of Life Science Frontiers, Kyoto University, Japan 'Gives an overview of the applications of single-molecule techniques in the biological sciences. It addresses topics as diverse as super-resolution microscopy (far beyond the Abbe limit) and the study of protein mechanics without ensemble averaging, and, due to its compact size, is informative reading for students and experts alike.' Lothar Kador, Professor of Physics, University of Bayreuth, Germany 'You will learn about the birth of detection of individual biomolecules, associated state-of-the-art technologies, cutting-edge research, and potential medical applications, all from a single-molecule point of view that will inform your new biological thoughts and insights.' Katsuyuki Shiroguchi, Principal Investigator, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan Author InformationKrishnarao Appasani is the Founder and Chief Executive Officer of GeneExpression Systems, a global conference-producing organisation focusing on biomedical and physical sciences. He is also an elected Life Fellow of the Royal Society of Biologists, London, UK. Raghu Kiran Appasani is a Psychiatrist and Neuroscientist. He practices at University of Southern California. He is also the Founder and Chief Executive Officer of The MINDS Foundation. Tab Content 6Author Website:Countries AvailableAll regions |
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