Historical Contributions to the Human Toxicology of Atropine

Author:   Ephraim Goodman ,  James S Ketchum ,  Reid D Kirby
Publisher:   Eximdyne
ISBN:  

9780967726434


Pages:   120
Publication Date:   19 May 2010
Format:   Hardback
Availability:   Out of print, replaced by POD   Availability explained
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Historical Contributions to the Human Toxicology of Atropine


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Overview

This monograph reviews selected aspects of the clinical syndrome produced by atropine intoxication, with particular reference to behavioral disturbances manifested therein. A human LD50 dose is estimated to be 453 mg, with 95% confidence limits of 335 - 612 mg (probit slope 1.8), for orally ingested atropine. The range of individual differences in behavioral toxicity and in lethality is described. Routes of administration of atropine are discussed, and some attempt is made to correlate dose-response data for the various routes. Finally, an historical summary of the military applications of the behavioral toxicology of atropine is presented with an Afterword on later research on atropine-related military incapacitants, viz. the chemical warfare agent BZ.

Full Product Details

Author:   Ephraim Goodman ,  James S Ketchum ,  Reid D Kirby
Publisher:   Eximdyne
Imprint:   Eximdyne
Dimensions:   Width: 15.60cm , Height: 0.80cm , Length: 23.40cm
Weight:   0.349kg
ISBN:  

9780967726434


ISBN 10:   0967726433
Pages:   120
Publication Date:   19 May 2010
Audience:   General/trade ,  General
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of print, replaced by POD   Availability explained
We will order this item for you from a manufatured on demand supplier.

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