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OverviewThis book discusses the efficacy of nanomaterial-based X-rays enhancers against cancer therapy and imaging in both in vitro and in vivo systems. Also, synthesis, mechanism, and the related biological effects are given. Moreover, nanoparticle-based contrast agents to enhance the image quality are compiled. Finally, special nanoparticle-based contrast agents to enhance the contrast for targeted cancer therapy are covered and discussed. Full Product DetailsAuthor: Surender Kumar Sharma , Hamed Nosrati , Taras KavetskyyPublisher: Springer International Publishing AG Imprint: Springer International Publishing AG Edition: 1st ed. 2022 Weight: 0.698kg ISBN: 9783031040702ISBN 10: 3031040708 Pages: 309 Publication Date: 01 November 2022 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsChapter 1. Application of X-ray in medicine and X-ray-sensitive materials Hamed RezaeeJam 1, Fatemeh Abhari 2, Surender Kumar Sharma3,4, Hamed Nosrati5 1Department of Radiology, School of Paramedical Sciences, Zanjan University of Medical Sciences, Zanjan, Iran. 2Faculty of Medicine, Department of Medical Physics, Tabriz University of Medical Sciences, Tabriz, Iran. 3Department of Physics, Federal University of Maranhao, Sao Luis, Brazil 4Department of Physics, Central University of Punjab, India 5Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Drohobych, Ukraine, Baku, Azerbaijan Table of Content: 1. Introduction 2. Radiotherapy 3. Imaging 4. X-ray-sensitive materials 4.1. Organic materials 4.2. Inorganic materials 4.3. Organic and inorganic hybrid materials 5. Challenges and future scope Chapter 2. Radiosensitizers Hossein Rahimi 1, Hamed Nosrati 1,2, Surender Kumar Sharma3,4, Hossein Danafar1 1Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan 45139- 56184, Iran. 2Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Drohobych, Ukraine, Baku, Azerbaijan. 3Department of Physics, Federal University of Maranhao, Sao Luis, Brazil 4Department of Physics, Central University of Punjab, India Table of Content: 1. Introduction 2. Small Molecules 2.1. Oxygen and its Mimics 2.2. Other chemical radiosensitizers 3. Macromolecules 3.1. MicroRNAs 3.2. Proteins and Peptides 3.3. Oligonucleotides and siRNAs 4. Challenges and future scope Chapter 3. Key Parameters in nanoparticles based radiotherapy Céline Frochot 1, Muriel Barberi-Heyob 2, Magali Toussaint2 1Université de Lorraine, LRGP, UMR 7274, 1 rue Grandville, Nancy, 54000, France 2Université de Lorraine, CRAN, UMR 7039, Campus Sciences, BP 70239, Vandoeuvre-lès-Nancy Cedex, 54506, France Table of Content: 1. Introduction 2. Key factors that shoud be measured 2.1. In vitro assessment 3. Biological evaluation methodology 4. The energy of X-rays 5. Irradiation setup 6. Interactions of X-rays with functionalized nanoparticles 7. Challenges and future scope Chapter 4. Nanoradiosensitizers Murat Barsbay, and Mohammadreza Ghaffarlou Hacettepe University, Department of Chemistry, Beytepe, Ankara 06800, Turkey. Table of Content: 1. Introduction 2. Physical aspect 3. Biological aspect 4. Metal based nanoradiosensitizers 4.1 Au based nanoradiosensitizers 4.2. Bi based nanoradiosensitizers 4.3. Other type nanoradiosensitizers 5. Heterostructured nanoradiosensitizers 6. Challenges and conclusion Chapter 5. Nanoparticles for overcome Hypoxia Yaqin Wang1,2, Wenting Shang2 1Department of Interventional Radiology, The First Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China. 2Chinese Academy of Sciences Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, People’s Republic of China. Table of Content: 1. Introduction 2. Targeting hypoxia by nanomedicine 3. Tumor oxygenation by nanomedicine 3.1. Oxygen loaded nanocarriers 3.2. Oxygen generators 4. Hypoxic-active nanoparticles as radiosensitizers 4.1. Nitroimidazoles 4.2. Sanazole 5. Summary and outlook Chapter 6. X-Ray based combination therapy Rovshan Khalilov1,2, Hamid Rashidzadeh1 1Department of Biophysics and Molecular Biology, Baku State University, Baku, Azerbaijan 2Russian Institute for Advanced Study, Moscow State Pedagogical University, 1/1, Malaya Pirogovskaya St, Moscow 119991, Russian Federation Table of Content: 1. Introduction 2. Combined Chemo-Radiotherapy 3. Combined Immune-Radiotherapy 4. Combined Photo-Radiotherapy 5. Summary and outlook Chapter 7. X-Ray triggered Photodynamic therapy Ali Mohammadi 1, Hamed Nosrati 2, Surender Kumar Sharma3,4, Taras Kavetskyy2,5 1Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan 45139- 56184, Iran. 2Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Drohobych, Ukraine, Baku, Azerbaijan. 3Department of Physics, Federal University of Maranhao, Sao Luis, Brazil 4Department of Physics, Central University of Punjab, India 5Department of Surface Engineering, The John Paul II Catholic University of Lublin, 20-950 Lublin, Poland Table of Content: 1. Introduction 2. X-ray-induced sensitizers 3. Rare-earth-element-based X-ray-induced sensitizers 4. Quantum dot-based X-ray-induced sensitizers 5. Silicon-based X-ray-induced sensitizers 6. Metal-based X-ray-induced sensitizers 7. Challenges 8. Summary and outlook Chapter 8. X-ray tomography contrast agents Mümin Mehmet Koç1,2, Naim Aslan3 1School of Engineering, University of Portsmouth, Portsmouth, United Kingdom 2Department of Physics, Kirklareli University, Kirklareli, Turkey 3Department of Metallurgical and Materials Engineering, Munzur University, Tunceli, Turkey. Table of Content: 1. Introduction 2. Molecule based contrast agents 2.1. Iodine-based contrast agents 2.2. Phosphotungstic acid 2.3. Phosphomolybdic acid 2.4. Osmium tetroxide 3. Nanoparticle based contrast agents 3.1 Gold nanoparticle based contrast agents 3.2 Silver nanoparticle based contrast agents 3.3. Bi nanoparticle based contrast agents 3.4. Thorium Oxide nanoparticle based contrast agents 3.5. Tantalum nanoparticle based contrast agents 3.6. Rare Earth nanoparticles based contrast agents 4. Summary Chapter 9. Radioprotectors Dmitry Klokov1,2 1Laboratory of Radiobiology and Radiotoxicology, Department of Research on Biological and Health Effects of Ionizing Radiation, Institute of Radioprotection and Nuclear Safety (IRSN), Fontenay-aux-Roses, France. 2Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada Table of Content: 1. Introduction 2. Molecular Radioprotectors Delivery by Nanocarriers 2.1. Organic polymeric carriers 2.2. Inorganic carriers 3. Nano Radioprotectors 3.1. Principle 3.2. The Common Nanoradioprotectors 3.2.1. Carbon-Based Nanoradioprotectors 3.2.2. Cerium-Based Nanoradioprotectors 3.2.3. Noble Metal Nanoradioprotectors 4. Summary and outlook Chapter 10. Reactive Oxygen Species (ROS)-Based Radiotherapy: a recent update Andreyan N. Osipov1, Margarita Pustovalova2 1State Research Center A. I. Burnazyan Federal Medical Biophysical Center of Federal Medical-Biological Agency of Russia, Moscow, Russia 2State Research Center Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia Table of Content: 1. Introduction 2. ROS Chemistry 3. ROS Biology 4. ROS Nanotechnology 5. Future scope and prospectiveReviewsAuthor InformationDr. Sharma is a Faculty Member in Physics at Department of Physics, Central University of Punjab, Bathinda, India. His research interests include magnetic nanohybrids, luminescent nanomaterials, optical properties, nanothermometry, thermal therapy, and bioimaging. Dr. Nosrati is the International Project Advisor & Developer of Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems (JUAI-REC-NBFN). His research includes the design and synthesis of functional bio-organic and metallic nanoboimaterials for theranostic applications as well as for enhanced chemo and X-ray radiation therapy of cancer. Dr. Kavetskyy is Associate Professor of Chemistry at the Department of Biology and Chemistry and Head of Materials of Solid-State Microelectronics Laboratory of Drohobych Ivan Franko State Pedagogical University, Ukraine, and Adiunkt (Assistant Professor) at the Department of Surface Engineering of The John Paul II Catholic University of Lublin, Poland. He is also Supervisor of Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems in Ukraine and Scientific Secretary of Expert Committee of Scientific Society of The Ministry of Education and Science of Ukraine, Section “Scientific Problems of Materials Science”. His current research interests are glasses, polymers, complex compounds, biomaterials, biosensors, nanosensors, radiation effects, carbon nanostructures, metal nanoparticles, ion implantation, and positron annihilation. Tab Content 6Author Website:Countries AvailableAll regions |
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