Overview

Through the integration of bioinformatic, genetic, transcriptomic, proteomic, metabolomic, phenomic and other massive datasets, genomics is revealing exciting new insights into fungal cell biology. The central theme of this volume is the strong impact that genomics is having upon our understanding of fungal biology, across a wide range of species, including model yeasts (such as Saccharomyces cerevisiae and Schizosaccharomyces pombe), filamentous fungi (such as Neurospora crassa and Aspergillus nidulans) and pathogenic fungi (such as Magnaporthe grisae, Candida albicans, Cryptococcus neoformans and Histoplasma capsulatum). World-renowned scientists address the following topics in these fungi: systems biology and evolution, circadian rhythms, apoptosis and stress responses, secretion, and environmental signalling networks. Particular emphasis is placed on fungal pathogenicity. Various genomic technologies are discussed, including genome-wide sequence comparisons, transcript profiling, proteomics, metabolomics and bioinformatics.

Full Product Details

Author:   Alistair J. P. Brown
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of hardcover 1st ed. 2006
Volume:   13
Weight:   0.645kg
ISBN:  

9783642065002

ISBN 10:   3642065007
Pages:   276
Publication Date:   12 February 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Fungal Systems Biology and Evolution 1 Metabolomics and Systems Biology in Saccharomyces cerevisiae J.I. Castrillo and S.G. Oliver 2 Genome Evolution in Hemiascomycete Yeasts L.J. Montcalm and K.H. Wolfe 3 Investigating the Evolution of Fungal Virulence by Functional Genomics S. Ahmad, D.M. Soanes, M.C. Barooah and N.J. Talbot Fungal Rhythms and Responses 4 Circadian Rhythms, Photobiology and Functional Genomics in Neurospora J.J. Loros and J.C. Dunlap 5 Genomics of Protein Secretion and Hyphal Growth in Aspergillus D.B. Archer and G. Turner 6 The Genomics of Stress Response in Fission Yeast B.T. Wilhelm and J. Bahler 7 Programmed Cell Death and Apoptosis in Fungi M. Ramsdale 8 Genomic Analysis of Cellular Morphology in Candida albicans M. Whiteway and A. Nantel Fungal Pathogenicity 9 Postgenomic Approaches to Analyse Candida albicans Pathogenicity C.A. Munro, C. Fradin, O. Bader and B. Hube 10 Integration of Metabolism with Virulence in Candida albicans A.J.P. Brown 11 Regulators of Candida glabrata Pathogenicity K. Haynes 12 Using Genomics to Study the Life Cycle of Histoplasma capsulatum A. Sil 13 Cryptococcus neoformans Pathogenicity R.T Nelson and J.K. Lodge Biosystematic Index Subject Index

Reviews

From the reviews: The book is split into three sections. ! this is a very interesting book and will find a space on my bookshelf. ! I am sure that I will be returning to it for initial information on a range of topics: the figures and references (including website resources) are particularly good. (A. Buddie, Bibliography of Systematic Mycology, Vol. 12 (3), 2007)

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