Overview

Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the invaluable cooperation of more than 40 scientists in the field of immunodeficiency. They focus both on the presenting features of patients with PIDs and on the required further investigation and management. Each of the numbered cases is followed by the questions, their answers, and additional discussion. Each question focuses on a particular aspect of the PID under consideration, and the topics covered include clinical diagnosis, laboratory findings, molecular mechanisms, and therapy.

Full Product Details

Author:   Asghar Aghamohammadi ,  Nima Rezaei
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2013 ed.
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   0.791kg
ISBN:  

9783642317842

ISBN 10:   3642317847
Pages:   380
Publication Date:   02 January 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Temporarily unavailable  
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Table of Contents

Recurrent infections.- Combined T- and B-cell immunodeficiencies.- Primary Antibody Deficiencies.- Disorders of Phagocytic Cells.- Immune dysregulation diseases.- Defects in Innate immunity: Receptors and Signaling Components.- Autoinflammatory disorders.- Complement deficiencies.- Other well-defined immunodeficiency syndromes.

Reviews

From the reviews: This book reviews some of the most common and important primary immunodeficiency syndromes through a series of selected cases that highlight the presenting clinical characteristics, diagnostic evaluation, including the molecular basis of the disorders, and basic treatment. ... This would be a good resource for general practitioners, pediatricians, infectious disease specialists, or hematologists who may encounter these patients. ... This book is a resource for nonimmunologists to help them recognize the clinical presentation of the primary immunodeficiency diseases. (Kari Neemann, Doody's Book Reviews, August, 2013)

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