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OverviewSpiro-Pyrrolidine-Oxindole is a recurring structural element that has been identified in numerous alkaloids and pharmacologically active compounds. These spiro-fused ring systems embody stereochemical and structural complexities that continue to challenge the synthetic chemist. This book describes a novel enantioselective synthesis of the spiro-pyrrolidine-oxindole ring system in a highly convergent manner.The key steps for the synthesis involve 1,3-dipolar cycloaddition reaction to form the pyrrolidine ring system and radical reaction for the formation of quarternary center. The present synthesis is efficient and would allow preparation of a library of compounds for biological screening. Full Product DetailsAuthor: Sesha Sridevi Alluri , Chih-Hung Wang , Michael BertucciPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.50cm , Length: 22.90cm Weight: 0.122kg ISBN: 9783838355085ISBN 10: 3838355083 Pages: 76 Publication Date: 06 July 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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