Overview

This book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research. The use of yeasts as experimental eukaryotic models increasingly gained prominence when several Nobel Prizes in Physiology/Medicine and Chemistry were awarded for innovative research, using yeast strains to elucidate molecular mechanisms in a wide range of human physiological processes and diseases, such as autophagy, cell cycle regulation and telomerase activity. This book offers useful insights for scientists in yeast research, clinical scientists working with yeast infectious models and for industrial researchers using applied microbiology. 

Full Product Details

Author:   Isabel Sá-Correia
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   1st ed. 2019
Volume:   58
Weight:   0.454kg
ISBN:  

9783030130374

ISBN 10:   3030130371
Pages:   242
Publication Date:   14 August 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Industrial Applications and Model Systems.- Physiological genomics of multistress resistance in the yeast cell model and factory: focus on MDR/MXR transporters.- Mechanisms of yeast adaptation to wine fermentations.- Development of robust yeast strains for lignocellulosic bio-refineries based on genome-wide studies.- Physiological genomics of the highly weak-acid-tolerant food spoilage yeasts of Zygosaccharomyces bailii sensu lato.- Yeast genome-scale metabolic models for simulating genotype-phenotype relations.- Human Health and Disease.- Emerging mechanisms of drug resistance in Candida albicans.- Genome-wide response to drugs and stress in the pathogenic yeast Candida glabrata.- Lipidomics approaches: applied to the study of pathogenesis in Candida species.- Yeast at the forefront of research on ageing and age-related diseases.

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