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OverviewPMHigh Quality Content by WIKIPEDIA articles! 48,XXYY syndrome is a sex chromosome anomaly in which males have an extra X and Y chromosome. Human cells usually contain two sex chromosomes, one from the mother and one from the father. Usually, females have two X chromosomes (XX) and males have one X and one Y chromosome (XY). The appearance of at least one Y chromosome makes a male. Therefore, XXYY only affects males. Males affected with XXYY syndrome have 48 chromosomes instead of the typical 46. This is why XXYY syndrome is sometimes written as 48,XXYY syndrome. It is estimated that XXYY affects one in every 18,000-40,000 male births. The first published report of a boy with a 48,XXYY karyotype was by Sylfest Muldal and Charles H. Ockey in Manchester, England in 1960. It was described in a 15-year-old mentally challenged boy who had signs of Klinefelter syndrome, however his chromosome testing showed 48,XXYY instead of 47,XX Full Product DetailsAuthor: Lambert M. Surhone , Miriam T. Timpledon , Susan F. MarsekenPublisher: VDM Publishing House Imprint: VDM Publishing House Dimensions: Width: 22.90cm , Height: 0.50cm , Length: 15.20cm Weight: 0.153kg ISBN: 9786131100864ISBN 10: 6131100861 Pages: 96 Publication Date: 02 August 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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