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OverviewHigh Quality Content by WIKIPEDIA articles! XPB (Xeroderma Pigmentosum B) is an ATP dependent human DNA helicase that is a part of the TFIIH transcription factor complex. The 3D structure of the archeael homologue of XPB has been solved by X-ray crystallography by Dr. John Tainer and his group at The Scripps Research Institute. XPB plays a significant role in normal basal transcription, transcription coupled repair (TCR), and nucleotide excision repair (NER). Purified XPB has been shown to unwind DNA with 3'-5'polarity. Mutations in XPB and other related complementation groups, XPA-XPG, leads to a number of genetic disorders such as Xeroderma Pigmentosum, Cockayne's syndrome, and Trichothiodystrophy. Full Product DetailsAuthor: Lambert M. Surhone , Miriam T. Timpledon , Susan F. MarsekenPublisher: VDM Publishing House Imprint: VDM Publishing House Dimensions: Width: 22.90cm , Height: 0.30cm , Length: 15.20cm Weight: 0.108kg ISBN: 9786131061578ISBN 10: 6131061572 Pages: 64 Publication Date: 28 July 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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