Overview

This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural components, genome packaging and maturation into an infectious virion. Each chapter will describe the components of the respective machine in molecular or atomic detail, genetic and biochemical analyses, and mechanism. Topics are carefully selected so that the reader is exposed to systems where there is a substantial infusion of new knowledge in recent years, which greatly elevated the fundamental mechanistic understanding of the respective molecular machine. The authors will be encouraged to simplify the detailed knowledge to basic concepts, include provocative new ideas, as well as design colorful graphics, thus making the cutting-edge information accessible to broad audience.

Full Product Details

Author:   Michael G. Rossmann ,  Venigalla B. Rao
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2012
Volume:   726
Dimensions:   Width: 17.80cm , Height: 4.30cm , Length: 25.40cm
Weight:   1.503kg
ISBN:  

9781461409793

ISBN 10:   1461409799
Pages:   687
Publication Date:   26 December 2011
Audience:   College/higher education ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Awaiting stock  
The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you.

Table of Contents

Viruses: Sophistiated Biological Machines.- F1-Atpase: A Prototypical Molecular Motor.- Reconstructing Virus Structures From Nanometer To Near-Atomic Resolutions With Cryo-Electron Microscropy And Tomography.- Principles Of Virus Structural Organization.- Viral Entry Machines.- Genome Replication Machines.- Capsid Assembly And Maturation.- Genome Packaging Machines.

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