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Author:   Jane Nikles ,  Geoffrey Mitchell
Publisher:   Springer
Imprint:   Springer
Edition:   1st ed. 2015
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   5.619kg
ISBN:  

9789401771993

ISBN 10:   9401771995
Pages:   245
Publication Date:   14 October 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Preface.- Introduction.- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences.- N-of-1 trials in medical contexts.- Aggregated N-of-1 trials.- Methodological considerations for N-of-1 trials.- Randomization, allocation concealment and blinding.- Data collection and quality control.- Individual reporting of N-of-1 trials to patients and clinicians.- Assessing and reporting adverse events.- Research ethics and N-of-1 trials.- Statistical analysis of N-of-1 trials.- The economics of N-of-1 trials.- Reporting N-of-1 trials to professional audiences.- Single patient open trials.- Systematic review and meta-analysis using N-of-1 trials.- Where are N-of-1 trials headed?- Index.

Reviews

“This is a philosophical rethinking of the limitations of randomized controlled trials and the value of cross-over experiments conducted with a single patient. … This is a book for experienced clinicians who are knowledgeable about current evidence-based treatment modalities and who can objectively recognize when to consider different options for treatment.” (Vincent F. Carr, Doody’s Book Reviews, January 2016)

This is a philosophical rethinking of the limitations of randomized controlled trials and the value of cross-over experiments conducted with a single patient. ... This is a book for experienced clinicians who are knowledgeable about current evidence-based treatment modalities and who can objectively recognize when to consider different options for treatment. (Vincent F. Carr, Doody's Book Reviews, January 2016)

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