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OverviewInnovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development.The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key experimental methods (calorimetry, surface plasmon resonance, NMR and X-ray crystallography) used in generating interaction data. The second half of the book is devoted to in-silico methods of modeling and predicting molecular recognition and binding. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them.With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of protein-ligand interaction modeling and analysis for both novices and experts. Full Product DetailsAuthor: Holger Gohlke (University of Dusseldorf, Ge)Publisher: Wiley-VCH Verlag GmbH Imprint: Wiley-VCH Verlag GmbH ISBN: 9781280662898ISBN 10: 1280662891 Pages: 361 Publication Date: 01 June 2012 Audience: General/trade , General Format: Electronic book text Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |