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OverviewThe present book is aimed to screen the potent lovastatin producing pair from a variety of solid substrates and fungal organisms. Lovastatin is a potent competitive inhibitor of HMG-CoA reductase, a microsomal enzyme that catalyzes the conversion of the substrates HMG-CoA to mevalonate. This enzyme has a significant role in the synthesis of cholesterol. Besides this, lovastatin has many biomedical applications. Lovastatin yield can be increased through solid state fermentation when compared to submerged fermentation and very few works have been carried oaut for the production of lovastatin through SSF. Substrates not used earlier were used to study the production of lovastatin. The work is planned under the five following objectives: 1.Screening of potential Lovastatin producing Fungal organisms and Solid substrates. 2.Optimizing the Process parameters and Nutrient parameters to increase the Lovastatin producing potential. 3.To immobilize Penicillium funiculosum by entrapment method. 4.Strain Improvement by using Physical and Chemical mutagens for better lovastatin production. 5.Antimicrobial activity of Lovastatin was performed to evaluate the antimicrobial activity. Full Product DetailsAuthor: Latha Dunga Prasanna , Hemalatha K P JPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 1.30cm , Length: 22.90cm Weight: 0.340kg ISBN: 9783659795725ISBN 10: 3659795720 Pages: 228 Publication Date: 12 January 2016 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |