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OverviewProdrugs are substances administered in an inactive form that is then metabolized in the body in vivo into the active compound. The rationale behind administering prodrugs is to optimize absorption, distribution, metabolism, and excretion of these drugs. Since first described in the 1950s, prodrugs continue to be a fertile area of research. There are a number of small pharmaceutical/biotech companies dedicated to using prodrugs for the delivery of older but problematic drugs as well as to developing broad-based prodrug technologies for application to new and future drugs. These volumes represent a comprehensive guide to prodrugs and will guide the reader through the current status of the prodrug concept and its many applications and to highlight its many successes in overcoming formulation and delivery of problematic drugs. Full Product DetailsAuthor: Valentino J Stella (Univ. of Kansas University of Kansas University of Kansas Univ. of Kansas Univ. of Kansas Univ. of Kansas University of Kansas Univ. of Kansas) , Ronald T Borchardt , Michael J Hageman , Reza OliyaiPublisher: Springer Imprint: Springer ISBN: 9781281493880ISBN 10: 1281493880 Pages: 1445 Publication Date: 01 January 2007 Audience: General/trade , General Format: Electronic book text Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |