Overview

Pore-forming toxins are virulence factors produced by a great variety of pathogenic bacteria ranging from the Gram-positive Staphylococcus aureus to the Gram-negative Helicobacter pylory. The recent studies reviewed in this volume describe the progress that has been made in dissecting the different steps of the mode of action of these proteins which generally include binding to specific cell surface receptors, oligomerization into ring like structures and membrane perforation.

Full Product Details

Author:   Gisou van der Goot
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2001
Volume:   257
Dimensions:   Width: 15.50cm , Height: 1.00cm , Length: 23.50cm
Weight:   0.285kg
ISBN:  

9783642625459

ISBN 10:   3642625452
Pages:   168
Publication Date:   20 November 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

List of Contents.- Pore-Forming Bacterial Protein Toxins: An Overview.- The Cholesterol-Dependent Cytolysins.- Aerolysin from Aeromonas hydrophila and Related Toxins.- Staphylococcal Pore-Forming Toxins.- RTX Toxin Structure and Function: A Story of Numerous Anomalies and Few Analogies in Toxin Biology.- Helicobacter pylori Vacuolating Cytotoxin: Cell Intoxication and Anion-Specific Channel Activity.- Pore-Forming Colicins and Their Relatives.

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