Overview
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
Full Product Details
Publisher: Birkhauser Basel
Imprint: Birkhauser Basel
ISBN: 9781282824850
ISBN 10: 1282824856
Pages: 289
Publication Date: 01 January 2009
Audience:
General/trade
,
General
Format: Electronic book text
Publisher's Status: Active
Availability: In stock
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