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OverviewHigh Quality Content by WIKIPEDIA articles! Transcriptional repressor NF-X1 is a protein that in humans is encoded by the NFX1 gene. MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN- . Three alternative splice variants, each of which encodes a different isoform, have been identified. Full Product DetailsAuthor: Lambert M. Surhone , Mariam T. Tennoe , Susan F. HenssonowPublisher: VDM Publishing House Imprint: VDM Publishing House Dimensions: Width: 22.90cm , Height: 0.60cm , Length: 15.20cm Weight: 0.168kg ISBN: 9786131346538ISBN 10: 6131346534 Pages: 106 Publication Date: 19 August 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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