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OverviewESBLs are known as extended-spectrum because they are able to hydrolyze a broader spectrum of beta- lactam antibiotics than the simple parent beta- lactamases from which they are derived. Such ESBLs have also the ability to inactivate beta-lactam antibiotics containing an oxyimino-group such as oxyimino-cephalosporins (eg; ceftazidime, ceftriaxone, cefotaxime) as well as oxyimino- monobactam. Furthermore, they are not active against cephamycins and carbapenems. Generally, they are inhibited by beta-lactamase-inhibitors such as clavulanate and tazobactam. ESBLs have been found in a wide range of Gram-negative rods. However, the vast majority of strains expressing these enzymes belong to the Enterobacteriaceae family. K.pneumoniae remains as the major ESBL-producer. Full Product DetailsAuthor: Sobhan Ghafourian , Sekawi Z , Sadeghifard NPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 1.30cm , Length: 22.90cm Weight: 0.336kg ISBN: 9783844317312ISBN 10: 3844317317 Pages: 224 Publication Date: 18 March 2011 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: Out of print, replaced by POD  We will order this item for you from a manufatured on demand supplier. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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