Overview

The 40th volume of Methods in Microbiology focuses on microbial synthetic biology.Synthetic biology is a rapidly growing discipline that builds on well-established principles of genetic engineering and biotechnology by integrating computational and engineering approaches to the design and construction of novel biological systems.This volume addresses some of the major technical challenges stand in the way of achieving a radical step-change in our ability to engineer complex multi-scaled biological systems. These include: the application of computation intelligence to the design of synthetic microbial systems, design automation and constraints; the impact of noise and stochasticity; the engineering of biosensors; the characteristic of a model bacterial chassis. A key issue in Synthetic Biology is that of its social dimensions and a chapter is dedicated to the important issue.

Full Product Details

Author:   Colin Harwood (Newcastle University, UK) ,  Anil Wipat (University of Newcastle upon Tyne)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Volume:   40
Dimensions:   Width: 19.10cm , Height: 1.80cm , Length: 23.50cm
Weight:   0.640kg
ISBN:  

9780124170292

ISBN 10:   0124170293
Pages:   240
Publication Date:   25 November 2013
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Computational Intelligence in the Design of Synthetic Microbial Genetic Systems Jennifer S. Hallinan 2. Constraints in the Design of the Synthetic Bacterial Chassis Antoine Danchin and Agnieszka Sekowska 3. Social Dimensions of Microbial Synthetic Biology Jane Calvert and Emma Frow 4. Bacillus Subtilis: Model Gram-positive Synthetic Biology Chassis Colin R. Harwood, Suzanne Pohl, Wendy Smith and Anil Wipat 5. Engineering Microbial Biosensors Lisa Goers, Nicolas Kylilis, Marios Tomazou, Ke Yan Wen, Paul Freemont and Karen Polizzi 6. Noise and Stochasticity in Gene Expression – A Pathogenic Fate determinant Mikkel Girke Jørgensen, Renske van Raaphorst and Jan-Willem Veening 7. Platforms for Genetic Design Automation Chris J. Myers

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Colin Harwwod is a professor at Newcastle University

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