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OverviewHigh Quality Content by WIKIPEDIA articles! IKK- is an enzyme that serves as a protein subunit of I B kinase, which is a component of the cytokine-activated intracellular signaling pathway involved in triggering immune responses. Its activity causes activation of a transcription factor known as Nuclear Transcription factor kappa-B or NF- B. Activated IKK- phosphorylates a protein called the inhibitor of NF- B, I B (I B ), which binds NF- B to inhibit its function. Phosphorylated I B is degraded via the ubiquitination pathway, freeing NF- B, and allowing its entry into the nucleus of the cell where it activates various genes involved in inflammation and other immune responses. Full Product DetailsAuthor: Lambert M. Surhone , Mariam T. Tennoe , Susan F. HenssonowPublisher: VDM Publishing House Imprint: VDM Publishing House Dimensions: Width: 22.90cm , Height: 0.90cm , Length: 15.20cm Weight: 0.236kg ISBN: 9786131269226ISBN 10: 613126922 Pages: 154 Publication Date: 15 August 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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