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OverviewThe genomic contents of 10 clinical bloodstream infection-associated E. coli strains, isolated at the Leicester Royal Infirmary were investigated in this study. Approaches used to investigate the genomic contents of these strains were: sequential PCR strategy, and the Microarray-Assisted mobilome Prospecting (MAmP). The study proved that such strategies are successful in addressing and identifying mobilome-rich strains. Therefore, using such approaches in combination with whole genome sequencing projects could prioritize the strains and the genomic regions that need to be sequenced. Such prioritization would avoid sequencing of hundreds of isolates to identify their novel gene pool and would reduce the cost of genomic sequencing. Moreover, applying such approaches for the identification of new virulence genes and/or pathogenic mechanisms could lead to significant improvements in the treatment of E. coli infections. Full Product DetailsAuthor: Bin Thani AliPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 1.10cm , Length: 22.90cm Weight: 0.281kg ISBN: 9783659607080ISBN 10: 3659607088 Pages: 188 Publication Date: 02 October 2014 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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