Overview

This is the first book on tularemia. With the biodefense initiative, there has been a major boost by the NIH to fund studies on bioterrorism agents, including Francisella, which is classified as a A bioterrorism agent. With the major interest in biodefense and the major threats of bioterrorism, Francisella tularensis has become a major interest for microbiologists, cell biologists, immunologists, and infectious disease experts. The volume explores the mechanisms of pathogenesis, genetics and genetic manipulations, genomics and metagenomics, identification of vaccine candidates, animal models to study the disease process, mechanisms of protective immunity, pathophysiology, vaccine development, genetic susceptibility, more effective therapies, clinical diagnosis, and routine and rapid microbiological diagnostic tools. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member

Full Product Details

Author:   Yousef Abu Kwaik ,  Dennis W. Metzger ,  Francis Nano ,  Anders Sjostedt
Publisher:   New York Academy of Sciences
Imprint:   New York Academy of Sciences
Dimensions:   Width: 15.40cm , Height: 1.70cm , Length: 21.90cm
Weight:   0.692kg
ISBN:  

9781573316910

ISBN 10:   1573316911
Pages:   430
Publication Date:   23 July 2007
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Stock Indefinitely
Availability:   Out of stock  

Table of Contents

Preface. 1. Tularemia: History, Epidemiology, Pathogen Physiology, and Clinical Manifestations: Anders Sjostedt. 2. Molecular Ecology, Epidemiology and Evolution of Francisella: Paul Keim, Anders Johannson, and David Wagner. 3. Genetics and Genetic Manipulations in Francisella Tularensis: Tom Zahrt and Dara Frank. 4. Francisella Tularensis: Genomics and Proteomics: Richard Titball and Joseph Petrosino. 5. The Francisella Pathogenicity Island: Francis E. Nano and Crystal Schmerk. 6. Molecular and Genetic Bases of Pathogenesis in Francisella Tularensis: Jeffrey R. Barker and Karl E. Klose. 7. Uptake and Intracellular Fate of Francisella Tularensis in Human Macrophages: Daniel Clemens and Marcus A. Horwitz. 8. Type II Secretion and Type IV Pili of Francisella: Tina Guina and Ake Forsberg. 9. The Structure and Function of Francisella LPS: John Gunn and Robert Ernst. 10. Francisella Tularensis Activation of the Inflammasome: David S. Weiss, Thomas Henry, and Denise M. Monack. 11. Animal Models of Francisella Tularensis Infection: C. Rick Lyons and Terry Wu. 12. Mucosal Immunopathogenesis of Francisella Tularensis: Dennis W. Metzger, Chandra Shekhar Bakshi, and Girish Kirimanjeswara. 13. Innate and Adaptive Immunity to Francisella: Karen L. Elkins, Siobhán C. Cowley, and Catharine M. Bosio. 14. Vaccines against Francisella Tularensis: J. Wayne Conlan and Petra C.F. Oyston. 15. Pneumonic Tularemia on Martha's Vineyard: Clinical, Epidemiologic and Ecological Characteristics: Bela T. Matyas, Henry S. Nieder, Sam R. Telford III. 16. New Approaches to Diagnosis and Therapy of Tularemia: Arne Tärnvik and May Chu. 17. Biosafety and Selectable Markers: Richard W. Titball, Anders Sjostedt, Martin S. Pavelka Jr., and Francis Nano. Index of Contributors

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions