Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents. NATO Science Series: II. Mathematics, Physics and Chemistry, Volume 245.

Author:   Randy J Read ,  Joel L Sussman
Publisher:   Springer
ISBN:  

9786610957897


Pages:   192
Publication Date:   01 January 2007
Format:   Electronic book text
Availability:   Out of stock   Availability explained
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Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents. NATO Science Series: II. Mathematics, Physics and Chemistry, Volume 245.


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Overview

X-ray crystallography is the pre-eminent technique for visualizing the structures of macromolecules at atomic resolution. These structures are central to understanding the detailed mechanisms of biological processes and to discovering novel therapeutics using a structure-based approach. Currently, structures are known for only a small fraction of the proteins encoded by human and pathogenic genomes. To counter the myriad modern threats of disease, there is an urgent need to determine the structures of the thousands of proteins whose structure and function remain unknown. This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.

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Author:   Randy J Read ,  Joel L Sussman
Publisher:   Springer
Imprint:   Springer
ISBN:  

9786610957897


ISBN 10:   6610957894
Pages:   192
Publication Date:   01 January 2007
Audience:   General/trade ,  General
Format:   Electronic book text
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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