Evaluation of Medicinal Plants & Shilajit for Anti-HIV Activity

Author:   Anuya Rege ,  Ramkrishna Ambaye ,  Ranjana Deshmukh
Publisher:   LAP Lambert Academic Publishing
ISBN:  

9783847324737


Pages:   224
Publication Date:   11 January 2012
Format:   Paperback
Availability:   In stock   Availability explained
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Evaluation of Medicinal Plants & Shilajit for Anti-HIV Activity


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Overview

Acquired Immunodeficiency Syndrome (AIDS) is a devastating human disease, caused by Human Immunodeficiency Virus (HIV). The development of safe, effective & low-cost Anti-HIV drugs is among the top global priorities of drug development, since the disease is not yet curable and the mortality is high. One of the strategies has been to identify Anti-HIV compounds from natural sources. In the present in vitro study, the material was selected on citations in the literature on Indian Traditional Medicine and also those commonly used in Folk Medicine. Total 17 extracts prepared from 5 plants namely, Ocimum sanctum, Withania somnifera, Tinospora cordifolia, Avicennia officinalis, Rhizophora mucronata & Shilajit a herbomineral have been evaluated for their specific inhibitory activity against HIV in vitro. The experimental results suggested that, most of the plants & Shilajit exert Anti-HIV activity via dual mechanism of action, viz., inhibiting viral Reverse Transcriptase (RT) enzyme & interfering with the gp120/CD4 interaction. Thus the present in vitro study forms a preliminary platform for further phytochemical & pharmacological evaluation.

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Author:   Anuya Rege ,  Ramkrishna Ambaye ,  Ranjana Deshmukh
Publisher:   LAP Lambert Academic Publishing
Imprint:   LAP Lambert Academic Publishing
Dimensions:   Width: 15.20cm , Height: 1.30cm , Length: 22.90cm
Weight:   0.336kg
ISBN:  

9783847324737


ISBN 10:   384732473
Pages:   224
Publication Date:   11 January 2012
Audience:   General/trade ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   In stock   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

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