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OverviewMultidrug-resistant (MDR) strains are serious threats to the control of tuberculosis and comprise an increasing public health problem. The worldwide increase in multidrug-resistant (MDR) tuberculosis has made the timely identification of resistant M. tuberculosis complex (MTBC) strains extremely important to achieve effective disease management. This study was performed with an objective to compare culture based proportion method with Genotype MTBDRplus reverse hybridization probe assay for identifying MDR-TB strains from suspected multi drug resistant cases, referred to GENETUP Kathmandu, Nepal. A commercially available new Genotype MTBDRplus assay (Hain Lifescince, GmBH, Nehern, Germany) was evaluated for its ability to detect mutations in Mycobacterial isolates conferring resistance to rifampin (RMP) and isoniazid (INH). MTBDRplus assay was designed to detect the mutations in the regulatory region of inhA. Full Product DetailsAuthor: Bimal DahalPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.70cm , Length: 22.90cm Weight: 0.186kg ISBN: 9783659153075ISBN 10: 3659153079 Pages: 120 Publication Date: 09 June 2012 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |