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OverviewThe goal of this book is to provide chemists and pharmacologists with the key information they need to answer questions such as: What opportunities for inhibitor interactions with enzyme targets arise from consideration of the catalytic reaction mechanism? How are inhibitors properly evaluated for potency, selectivity, and mode of action? What are the potential advantages and liabilities of specific inhibition modalities with respect to efficacy in vivo? And finally, what information should medicinal chemists and pharmacologist expect from their biochemistry/enzymology colleagues in order to most effectively pursue lead optimization? Full Product DetailsAuthor: Robert A Copeland (DuPont Pharmaceuticals Company Epizyme, Inc. and University of Pennsylvania)Publisher: John Wiley & Sons Imprint: John Wiley & Sons ISBN: 9781280255069ISBN 10: 1280255064 Pages: 294 Publication Date: 18 March 2005 Audience: General/trade , General Format: Electronic book text Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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