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OverviewCandida is an opportunistic commensal of the human oral, gastrointestinal, vaginal, cutaneous and mucosal surfaces. Risk factors that increase incidence of Candida infections are associated with compromised immunity. The currently available drugs have low efficacy, high toxicity and frequently lead to drug resistance. There is thus a critical need to develop more effective therapies to deal with such infections and natural products offer a safer alternative. Another useful strategy would be to improve the efficacy of the existing antifungal drugs using combinational therapy. Plant essential oils possess a broad spectrum of antimicrobial properties due to the presence of bioactive natural molecules. Eugenol, methyl eugenol, thymol and carvacrol are four such natural products. The present study is an attempt to examine the antifungal and antioxidant activity of these structurally related compounds. Combinational studies were also performed to investigate the use of chemo-sensitization by eugenol and derivatives to augment the efficacy of conventional antifungal drugs. Present study encourages the use of eugenol and its derivatives for the treatment and prevention of candidiasis. Full Product DetailsAuthor: Aijaz Ahmad , Luqman Khan , Nikhat ManzoorPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 1.40cm , Length: 22.90cm Weight: 0.358kg ISBN: 9783845470207ISBN 10: 3845470208 Pages: 240 Publication Date: 08 September 2011 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |