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Author:   G. E. Francis
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of the original 1st ed. 2000
Volume:   25
Dimensions:   Width: 15.20cm , Height: 1.80cm , Length: 22.90cm
Weight:   0.487kg
ISBN:  

9781489941718

ISBN 10:   1489941711
Pages:   318
Publication Date:   11 August 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Strategies.- Chemical Construction of Immunotoxins.- Construction of Ribonuclease–Antibody Conjugates for Selective Cytotoxicity.- Intracellular Targeting Using Bispecific Antibodies.- Antibody Conjugation Methods for Active Targeting of Liposomes.- Folate as a Targeting Device for Proteins Utilizing Folate Receptor-Mediated Endocytosis.- Preparation of Recombinant RNase Single-Chain Antibody Fusion Proteins.- Theoretical Aspects.- Practical Considerations in the Exploitation of Passive Tumor Targeting.- Effect of Dose, Molecular Size, and Binding Affinity on Uptake of Antibodies.- Inhibition of Tumor Blood Flow.- Applications.- 10 Targeting in Myocardial Infarction.- 11 Targeting HIV-Infected Cells.- 12 Making Fusion Toxins to Target Leukemia and Lymphoma.- Antibody-Bearing Liposomes as Chloroquine Vehicles in Treatment of Murine Malaria.- 14 Immunotargeting of Catalase to the Pulmonary Vascular Endothelium.- 15 Targeted Gene Transfer.

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