Overview

Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Full Product Details

Author:   Dennis M. Brown
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of hardcover 1st ed. 2004
Dimensions:   Width: 17.80cm , Height: 2.00cm , Length: 25.40cm
Weight:   0.765kg
ISBN:  

9781617372384

ISBN 10:   1617372382
Pages:   390
Publication Date:   19 November 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

I: Pharmacological Considerations for Drug Delivery Systems in Cancer Medicine.- 1 Systemically Administered Drugs.- 2 Regional Administration of Antineoplastic Drugs.- 3 Theoretical Analyses and Simulations of Anticancer Drug Delivery.- II: Technologies Available for Use in Cancer Drug Delivery Systems.- 4 Biopolymers for Parenteral Drug Delivery in Cancer Treatment.- 5 Hydrogels in Cancer Drug Delivery Systems.- 6 Microparticle Drug Delivery Systems.- 7 Polyethylene Glycol Conjugation of Protein and Small Molecule Drugs: Past, Present, and Future.- 8 Emulsions As Anticancer Delivery Systems.- III: Current Applications: Products Approved or in Advanced Clinical Development.- 9 Liposomal Drug Delivery Systems for Cancer Therapy.- 10 Gliadel®: A New Method for the Treatment of Malignant Brain Tumors.- 11 Intralesional Chemotherapy with Injectable Collagen Gel Formulations.- 12 Sustained-Release Drug Delivery with DepoFoam.- 13 Cancer Vaccines.- IV: Future Directions: Novel Cancer Drug Targets and Delivery Systems.- 14 Gene Therapy of Cancer.- 15 Progress in Antisense Technology.- 16 Tumor Vaccines.- 17 Diagnosis and Treatment of Human Disease Using Telomerase As a Novel Target.

Reviews

this book should serve as a valuable resource to anyone interested in the field of drug delivery systems in cancer therapy. It would be particularly useful to individuals developing novel agents that might benefit from selective packaging and delivery approaches. -Doody's Health Sciences Book Review Journal The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. - Tumori ...provide(s) concise and easily understandable clinical significance, current status, and future perspective of anticancer drug delivery. - Pharmaceutical Research

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