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OverviewDetection of transcription silencing sites in Mycobacterium TN provides us the best solutions in understanding the virulence encoded by the genome of M. leprae and immunity of the host against the pathogen. Genome analysis of various species of genus Mycobacterium has shown that there is little change in gene order among species and even in between strains of the same species. Sometimes it is same in all the strains. So, transcriptional and translational control of gene expression might be the reason for the differences between two strains of the same gene content and order. An attempt was made to recognize transcriptional active sites which play an important role in transcriptional silencing and thus regulating the gene expression at the level of transcription. While studying the genome of M.Leprae, it was found that there are approximately half of the genes expressed while the rest are transcriptionally inactive. Transcription silencing might be one of the reasons contributing to the differences in two organisms which may be having the same gene content and order and having different expression patterns, which also effect pathogencity of organism. Full Product DetailsAuthor: S K MavuriPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.40cm , Length: 22.90cm Weight: 0.100kg ISBN: 9783847340232ISBN 10: 3847340239 Pages: 60 Publication Date: 17 January 2012 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |