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OverviewThe US Environmental Protection Agency (EPA) Integrated Risk Information System (IRIS) program develops toxicologic assessments of environmental contaminants. IRIS assessments provide hazard identification and dose-response assessment information. The information is then used in conjunction with exposure information to characterize risks to public health and may be used in risk-based decisionmaking, in regulatory actions, and for other risk-management purposes. Since the middle 1990s, EPA has been in the process of updating the IRIS assessment of inorganic arsenic. In response to a congressional mandate for an independent review of the IRIS assessment of inorganic arsenic, EPA requested that the National Research Council convene a committee to conduct a two-phase study. Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic is the report of the first phase of that study. This report evaluates critical scientific issues in assessing cancer and noncancer effects of oral exposure to inorganic arsenic and offers recommendations on how the issues could be addressed in EPA's IRIS assessment. Full Product DetailsAuthor: Committee on Inorganic Arsenic , Board on Environmental Studies and Toxicology , Division on Earth and Life Studies , National Research CouncilPublisher: National Academies Press Imprint: National Academies Press ISBN: 9780309297066ISBN 10: 0309297060 Pages: 127 Publication Date: 20 December 2013 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of Contents1 Front Matter; 2 Summary; 3 1 Introduction; 4 2 Exposure Considerations; 5 3 IRIS Assessment Development Plans: Evidence Evaluation, Systematic Review, and Meta-analysis; 6 4 Hazard Identification; 7 5 Susceptibility Factors; 8 7 DoseResponse Analysis; 9 References; 10 Appendix A--Biosketches of the Committee on Inorganic Arsenic; 11 Appendix B--Workshop AgendaReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |