Overview

This revised and extended second edition focuses on current and emerging topics in drug development, their molecular mechanisms of action as well as regulatory issues. In addition, in-depth insights into clinical drug research and trial methodology are presented on the basis of concrete case studies. This updated book makes a valuable contribution to the field of Clinical Pharmacology and serves as a must-have guide for professors, researchers and advanced students from academia and pharmaceutical industry. 

Full Product Details

Author:   Markus Müller
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 2nd ed. 2016
Weight:   0.845kg
ISBN:  

9783319801186

ISBN 10:   331980118
Pages:   405
Publication Date:   25 April 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

The discipline of Clinical Pharmacology.- Current issues in drug development.- Current issues in drug regulation.- Current issues in drug reimbursement.- Ethics of clinical research.- GCP, Scientific misconduct.- Phases of drug development, first in man studies.- Clinical trials - Interventional studies.- Clinical trials - observational studies.- Imaging.- Microdosing.- Genomics.- Pharmacokinetics/Pharmacodynamics.- Epidemiology, statistics.- Placebo effects.- Pharmaceutical drug safety.- Drug interactions.- Advanced therapies.- Biological pharmaceuticals.- Generic drugs, Enantiomers.- Special situations I: orphan drugs.- Special situations II: sex differences.- Special situations III: children.

Reviews

The aim is to describe the role of the discipline of clinical pharmacology in drug discovery. ... The intended audience is faculty, researchers, and advanced students from academia and the pharmaceutical industry who are learning about or involved in the process of drug discovery. ... This book provides a multitude of very useful insights about the successes and failures in drug development for scientists who are, or will be, involved in the process of drug discovery. (Thomas L. Pazdernik, Doody's Book Reviews, May, 2016)

“The aim is to describe the role of the discipline of clinical pharmacology in drug discovery. … The intended audience is faculty, researchers, and advanced students from academia and the pharmaceutical industry who are learning about or involved in the process of drug discovery. … This book provides a multitude of very useful insights about the successes and failures in drug development for scientists who are, or will be, involved in the process of drug discovery.” (Thomas L. Pazdernik, Doody's Book Reviews, May, 2016)

Author Information

Prof. Markus Müller, MDRector of the Medical University of ViennaVienna, Austria

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