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OverviewFull Product DetailsAuthor: John E. MurphyPublisher: American Society of Health-System Pharmacists Imprint: American Society of Health-System Pharmacists Edition: 5th Revised edition Dimensions: Width: 17.80cm , Height: 2.50cm , Length: 25.40cm Weight: 0.739kg ISBN: 9781585282548ISBN 10: 1585282545 Pages: 434 Publication Date: 30 October 2011 Audience: Primary & secondary/elementary & high school , Educational: Primary & Secondary Format: Paperback Publisher's Status: Out of Print Availability: In Print  Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of ContentsReviewsClinical Pharmacokinetics, 5th Edition --Melissa M. Ranieri, BS, Pharm.D., MedInfoNow: Doody's Review Services (01/01/2012) <b><i>Clinical Pharmacokinetics, 5th Edition</b><b>edited by John E. Murphy.</b><b>The Pharmaceutical Journal; 2012; March 6th; Volume 288; Page 311</b>Laurence A. Goldberg is a pharmaceutical consultant from Bury, Lancashire <b> <b>Genes are only part of the story</b>This book has been written to help practitioners predict drug doses to achieve target drug concentrations from doses administered to patients. Important chapters on rational use of drug concentration measurements, dosing in overweight and obese patients, dosing considerations for a wider variety of drugs used in neonatal, paediatric and geriatric patients, drug dosing in renal disease and creatinine clearance estimation complete this fifth edition. It offers information for medicines that require an understanding of individual patients probable or actual drug concentrations to achieve medication effectiveness and safety.The authors have taken advantage of advances in knowledge to update the chapters. In many cases, more judicious monitoring of drug concentrations is suggested compared with the earlier editions. In some cases, the dosing approaches are radically different and, in others, new prediction approaches are available that have been tested in larger numbers of patients. Many chapters have been updated to take into account emerging pharmacogenetics knowledge.Typically, each chapter includes the usual dose range, the bioavailability of the dose forms, general pharmacokinetic information (absorption, distribution, elimination, metabolism, protein binding), clearance, volume of distribution, half-life and time to steady state, therapeutic range, dosing strategies, sampling times, pharmacodynamic monitoring, drug-drug interactions, pharmacodynamic interactions, drug-disease interactions and references.This book is an excellent reference source offering practitioners the key principles in pharmacokinetics and the application of these principles in drug therapy. Since the tables now comprise international and traditional units for drugs and laboratory tests, the book can be used across the world. All workers in this area of practice should have access to this fine work.--Laurence A. Goldberg The Pharmaceutical Journal (03/06/2012) Clinical Pharmacokinetics, 5th Editionedited by John E. Murphy.The Pharmaceutical Journal; 2012; March 6th; Volume 288; Page 311Laurence A. Goldberg is a pharmaceutical consultant from Bury, Lancashire Genes are only part of the storyThis book has been written to help practitioners predict drug doses to achieve target drug concentrations from doses administered to patients. Important chapters on rational use of drug concentration measurements, dosing in overweight and obese patients, dosing considerations for a wider variety of drugs used in neonatal, paediatric and geriatric patients, drug dosing in renal disease and creatinine clearance estimation complete this fifth edition. It offers information for medicines that require an understanding of individual patients probable or actual drug concentrations to achieve medication effectiveness and safety.The authors have taken advantage of advances in knowledge to update the chapters. In many cases, more judicious monitoring of drug concentrations is suggested compared with the earlier editions. In some cases, the dosing approaches are radically different and, in others, new prediction approaches are available that have been tested in larger numbers of patients. Many chapters have been updated to take into account emerging pharmacogenetics knowledge.Typically, each chapter includes the usual dose range, the bioavailability of the dose forms, general pharmacokinetic information (absorption, distribution, elimination, metabolism, protein binding), clearance, volume of distribution, half-life and time to steady state, therapeutic range, dosing strategies, sampling times, pharmacodynamic monitoring, drug-drug interactions, pharmacodynamic interactions, drug-disease interactions and references.This book is an excellent reference source offering practitioners the key principles in pharmacokinetics and the application of these principles in drug therapy. Since the tables now comprise international and traditional units for drugs and laboratory tests, the book can be used across the world. All workers in this area of practice should have access to this fine work.--Laurence A. Goldberg The Pharmaceutical Journal (03/06/2012) Author InformationJohn E. Murphy, PharmD, is Professor of Pharmacy Practice and Science and Associate Dean for Academic and Professional Affairs at the College of Pharmacy, and Professor of Clinical, Family and Community Medicine at the College of Medicine, the University of Arizona in Tucson. He is also an Honorary Professor at the University of Otago School of Pharmacy in Dunedin, New Zealand. Dr. Murphy served as Head of the Department of Pharmacy Practice and Science at the College of Pharmacy from 1991 to 2006. John received BS in pharmacy and PharmD degrees from the University of Florida in Gainesville, where he was a recipient of the Distinguished Pharmacy Alumnus Award in 1998. He spent 12 years on the faculty at Mercer University Southern School of Pharmacy in Atlanta, where he also served as Director of Pharmacokinetic Services at a 500 bed medical center.Long active in pharmacy organizations, Dr. Murphy was president of the American College of Clinical Pharmacy (ACCP) in 2008-2009. He served as president (1997-1998) and member of the Board of Directors (1994-1999) of the American Society of Health-System Pharmacists (ASHP) and as president of the Georgia Society of Hospital Pharmacists. John has been awarded fellow status in three organizations - ACCP, the American College of Clinical Pharmacology, and ASHP.Dr. Murphy has published over 200 papers, 90 abstracts, and four editions of Clinical Pharmacokinetics. John was Co-Director from 2000-2005 of the Arizona Clinical Research Training Program (AzCRTP), an NIH K30 Clinical Research Curriculum Award. His research interests include preventing drug-drug interactions, pharmacy education, and clinical pharmacokinetics. Among various professional and teaching awards received over the years, John was honored with the Award for Sustained Contributions to the Literature of Pharmacy Practice from the American Society of Health-System Pharmacists Foundation in 2003. 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