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OverviewPlease note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Chinese hamster ovary (CHO) cells are a cell line derived from the ovary of the Chinese hamster. They are often used in biological and medical research and commercially in the production of therapeutic proteins. They were introduced in the 1960s and grow as a cultured monolayer. They require the amino acid proline in their culture medium.CHO cells are used in studies of genetics, toxicity screening, nutrition and gene expression, particularly to express recombinant proteins. Today, CHO cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics.The use of the Chinese hamster in research began in 1919 where they were used in place of mice for typing pneumococci. They were subsequently found to be excellent vectors for transmission of kala-azar (also known as visceral leishmaniasis), facilitating research in epidemiology. Full Product DetailsAuthor: Lambert M. Surhone , Mariam T. Tennoe , Susan F. HenssonowPublisher: Betascript Publishing Imprint: Betascript Publishing Dimensions: Width: 15.20cm , Height: 0.40cm , Length: 22.90cm Weight: 0.131kg ISBN: 9786133545946ISBN 10: 6133545941 Pages: 80 Publication Date: 13 November 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: Out of print, replaced by POD  We will order this item for you from a manufatured on demand supplier. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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