Overview

"This monograph by Antonino Germano and Francesco Tomasello with contributions of Giuseppe Anastasi, Placido Bramanti, and Domenico d'Avella, constitutes a comprehensive, yet focused overview of those blood brain barrier permeability changes and related damaging sequelae associated with the presence of subarachnoid blood commonly linked to aneurysmal bleeding. As noted by the authors, despite improvements in the surgical and clinical management of aneurysms and their associated bleeding, these patients still experience an unacceptably high morbidity and mortality linked to the presence of subarachnoid blood. In this monograph, Dr. Germano and colleagues review the historical basis of this problem, providing detailed descriptions of the anatomical substrates of the blood-brain barrier, while discussing the occurrence and adverse consequences of barrier disruption following subarachnoid haemorrhage. The related sequelae of oedema formation, intracranial pressure alteration and vasospasm are discussed from both the basic science and clinical perspective, with the consideration of multiple clinical and laboratory investigative tools, including all aspects of modern imaging. The text is supplemented by tabular data presenting key research publications in the field, focusing on the damaging consequences of subarachnoid blood, while attempting to explain the hierarchy of events in those progressive changes associated with blood-brain barrier perturbation, including vasospasm, ischaemia and elevated intracranial pressure. The monograph also includes detailed consideration of Dr. Germano's research efforts in animals model using autologous arterial blood injected into the cisterna magna."""

Full Product Details

Author:   Antonio F. Germano ,  Francesco Tomasello
Publisher:   Springer Verlag GmbH
Imprint:   Springer Verlag GmbH
Edition:   Softcover reprint of the original 1st ed. 2001
Dimensions:   Width: 15.50cm , Height: 0.80cm , Length: 23.50cm
Weight:   0.238kg
ISBN:  

9783709172506

ISBN 10:   3709172500
Pages:   130
Publication Date:   16 September 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions