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OverviewThe objective of this work was to evaluate the suitability of in situ forming biodegradable microparticles for the controlled delivery of proteins. Particular goals were: a) to evaluate the flexibility of the release patterns of in situ implant and in situ microparticle formulations using hen egg white lysozyme as model protein; b) to characterize, if and how the integrity of the model protein is affected by formulation ingredients, the manufacturing process, sto-rage of the ISM and the release from the formulations; c) to optimize protein delivery from in situ forming implant and microparticle systems, with regard to shape and completeness of the release; d) to find / validate reliable methods allowing to extract and thus to characterize the model protein in biodegradable in situ formulations. Full Product DetailsAuthor: Martin KörberPublisher: VDM Verlag Dr. Mueller E.K. Imprint: VDM Verlag Dr. Mueller E.K. Dimensions: Width: 15.20cm , Height: 1.80cm , Length: 22.90cm Weight: 0.445kg ISBN: 9783639076592ISBN 10: 3639076591 Pages: 332 Publication Date: 22 August 2008 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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