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OverviewThe emergence of extended-spectrum beta-lactamase (ESBL)- and metallo-beta-lactamase (MBL)-producing bacteria causing lower respiratory tract infection (LRTI) has resulted in fewer therapeutic options in treatment modalities. No studies regarding MBLs had been done so far in Nepal and a few researches on ESBLs were also just pilot studies. Therefore, this study was carried out to determine the bacterial etiology of LRTI and to assess the current levels of antimicrobial resistance in Nepal. Combination disk and Double disk synergy test methods were used for the detection of ESBL- and MBL-producing bacteria. A high level of antibiotic resistance was seen. One-fourth of the gram-negative bacterial isolates were ESBL-producer. The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) was also relatively higher. Moreover, we isolated MBL-producing bacteria for the first time in Nepal. It is concluded that the problem of antimicrobial resistance is high in our set-up. It is essential to have effective antimicrobial and infection control policy in the hospital and special care should be taken to prevent the dissemination of the resistant clones to the community. Full Product DetailsAuthor: Shyam Kumar MishraPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 1.50cm , Length: 22.90cm Weight: 0.381kg ISBN: 9783659334146ISBN 10: 3659334146 Pages: 256 Publication Date: 25 October 2013 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |