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OverviewAdvances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Full Product DetailsAuthor: Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA) , Frederick W. Alt (Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA) , Frederick W. Alt (Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA) , Frederick W. Alt (Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Volume: v. 99 Dimensions: Width: 15.20cm , Height: 1.80cm , Length: 22.90cm Weight: 0.580kg ISBN: 9780123743251ISBN 10: 0123743257 Pages: 240 Publication Date: 18 December 2008 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of Contents1. Cis-Regulatory Elements and Epigenetic Changes Control Genomic Rearrangements of the IgH Locus Thomas Perlot and Frederick W. Alt 2. DNA-PK: The means to justify the ends? Katheryn Meek, Van Dang, and Susan P. Lees-Miller 3. Thymocyte selection including the new proteosome system Yousuke Takahama 4. Myocarditis Noel R. Rose 5. IL-17 Casey Weaver 6. TSLP and determinants of a Th2 host response Yong-Jun LiuReviewsThe series which all immunologists need. -THE PHARMACEUTICAL JOURNAL Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions. -SCIENCE Deserves a permanent place in biomedical libraries as an aid in research and in teaching. -JOURNAL OF IMMUNOLOGICAL METHODS Author InformationFrederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School. Tab Content 6Author Website:Countries AvailableAll regions |
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